ythA [2019-01-30 13:56:10]

cytochrome bd2, menaquinol oxidase (7:1 protons)

locus: BSU30710

pI: 9.42

mw: 48.49 kDa

protein length: 443 aa

gene length: 1332 bp

function: respiration

product: cytochrome bd2, menaquinol oxidase (7:1 protons)

essential: no

synonyms

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.1|Electron transport and ATP synthesis] → [category|SW 2.1.2|Respiration] → [category|SW 2.1.2.1|Terminal oxidases]
• [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.5|Newly identified sporulation proteins (based on transcription profiling)]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

Gene

Coordinates: 3,139,431 → 3,140,762

The protein

Paralogous protein(s)

• [protein|C0459C0D45E31561D281E016D86CD80DCAF13357|CydA]

Structure

• [PDB|5DOQ] (from Geobacillus thermodenitrificans, 42% identity)

Expression and Regulation

Operons

• genes: [gene|EB8AF295A11F28BDFAE39038FA89890824FC7791|ythA]-[gene|813E4BBEC8701114503ACD66DD6FE5A06B6B5E5F|ythB]-[gene|74DEE21BF65279A02A64EFCB60A06573F7C46B19|ytzL]
  description: [Pubmed|22383849]

  regulation

  • expressed during [SW|sporulation] [Pubmed|22383849]

Biological materials

Mutant

• MGNA-A291 (ythA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/291 NBRP B. subtilis, Japan]
• BKE30710 (Δ[gene|EB8AF295A11F28BDFAE39038FA89890824FC7791|ythA]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE30710 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACAATCGTAAACCACCTTT, downstream forward: _UP4_TAATGGCTCCGCAAACAGGA
• BKK30710 (Δ[gene|EB8AF295A11F28BDFAE39038FA89890824FC7791|ythA]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK30710 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACAATCGTAAACCACCTTT, downstream forward: _UP4_TAATGGCTCCGCAAACAGGA

References

• 11073895,10551842